By InTouch Weekly
Every TV show is only as good as its cast, and sometimes, it's entirely the cast that makes the show. Even if producers try to salvage the storyline after writing a lead character out of the script, things just aren't the same afterwards.
We all remember crying heaps when Mischa Barton's character, Marissa, was killed off in the series. Let's just say that was the high point of the storyline and everything was downhill from there...
While the show continued to be hilarious (right up until its conclusion), viewers could definitely feel Rob Lowe and Rashida Jones' absence.
Producers were faced with a major dilemma when it came to the future of ‘TAHM’ in the face of Charlie Sheen's downward media spiral. Nevertheless, it was clear after his departure that no one could replace him — not even Ashton Kutcher.
Tanned, fit bodies were aplenty when it came to 'Baywatch,' but apparently, it was blonde bombshell Pamela Anderson who anchored the show. Needless to say, the show was doomed without her.
Fans were shocked when Nina Dobrev announced her departure from 'The Vampire Diaries' — after all, she's kind of THE main female lead. Only time will tell if the show will survive without her, though we're not betting on it.
No more McDreamy—digest that for a moment. After so many years on the show, Patrick Dempsey's character was killed off in what could only be considered one of the most abrupt plot twists ever. How can the show possibly continue on without him?