Madonna is a material girl living in her material world — which apparently doesn’t have room for down-on-their-luck family members!

According to a new report, the 56-year-old’s brother, Anthony, is practically homeless, as he’s living out a Michigan garage and suffering from several broken ribs and complications from a fractured ankle — and Madge won’t do anything to help her sibling in need!

anthony ciccone

The superstar’s father, Tony, has urged his famous daughter (who is worth an estimated $500 million) to help her brother, who has found himself in a desperate situation. But she won’t budge — even though her brother Mario is the only one supporting her decision.

“Sadly the relationships appear to be beyond repair,” a source said. “Madonna and Mario are done with Anthony forever. They don’t think he deserves any more chances.”

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Madge took this tough-love stance after they met at the patriarch’s vineyard in Michigan to discuss how they can help their brother Anthony — who came to the meeting drunk.

At least one family member — sister Paula — isn’t giving up on Anthony, who believes his siblings think he “chose this lifestyle.”

“The truth is [Madonna] doesn’t care if I’m dead,” he confessed, adding he hasn’t seen his sister in a few years. “I doubt she’d even recognize me.”